BRCA1 and breast cancer: For BC surveillance in women with BRCA1/2 GPVs, the latest version of the National Comprehensive Cancer Network (NCCN) Clinical Practice Guidelines for Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic, Version 2.2022 (https://www.nccn.org/home, Last accessed on 16 April 2022) recommends BC awareness from an age of 18 years and clinical breast examination every 6–12 months from an age of 25 years.