BRCA1 and breast cancer: The odds ratios of BRCA1 and BRCA2 for BC risk were reported to be 10.57 and 5.85, respectively, by Dorling et al., and 7.62 and 5.23, respectively, by Hu et al. In addition, the odds ratios for female BRCA1 GPV carriers were higher for TNBC (56.80 and 42.88, respectively) than for ER-positive BC (3.92 and 3.39, respectively) (Table 1).