In agreement with previous data which we had described for the hepatic uptake transporters SLC22A1/OCT1 [67] and SLCO1B1/OATP1B1 [56] cholestasis, alcohol consumption, and inflammation determined by C-reactive protein altered SLC10A1/NTCP expression whereas age and gender are of minor importance. The gene discussed is SLC22A1; the disease is cholestasis.