Mutations in BEST1 have also been associated with other clinically distinct retinal degenerative diseases including Autosomal Recessive Bestrophinopathy (ARB), Autosomal Dominant Vitreoretinochoroidopathy (ADVIRC), Adult Vitelliform Macular Degeneration (AVMD), and Retinitis Pigmentosa 50 (RP50). This evidence concerns the gene BEST1 and autosomal dominant vitreoretinochoroidopathy.