BEST1 and autosomal recessive bestrophinopathy: Mutations in BEST1 have also been associated with other clinically distinct retinal degenerative diseases including Autosomal Recessive Bestrophinopathy (ARB), Autosomal Dominant Vitreoretinochoroidopathy (ADVIRC), Adult Vitelliform Macular Degeneration (AVMD), and Retinitis Pigmentosa 50 (RP50).