DRAM2 and retinal disorder: In the previous studies of DRAM2 retinopathy it was suggested that transcripts of variants in Patient 7 (p.Ser44Asn; p.Trp165*), Patients 8–18 (p.Gly47Valfs*3 homozygous), Patient 22 (p.Ala210GlufsTer16 homozygous) and Patient 24 (c.518-1G > A homozygous) create premature termination codons (PTC), which are eliminated by the nonsense-mediated mRNA decay (NMD) to avoid aberrant gene expression [12,13,15,43].