HSPB1 levels were found to be lower in caveolin-1-deficient breast cancer cells [36], and the treatment of keratinocytes with agents such as filipin or methyl-β-cyclodextrin that disrupt lipid raft-caveolae suppressed sulfur mustard-induced HSPB1 mRNA and protein expression [37]. This evidence concerns the gene HSPB1 and breast carcinoma.