Furthermore, IL-15 has also been integrated with other CARs for targeting different types of tumors, such as IL13Ra-CAR [81] and Fn14-CAR [82] for glioblastoma, GD2-CAR [83] for neuroblastoma, as well as Glypican-3 (GP3) CAR [84] for hepatocellular carcinoma (Table 4). This evidence concerns the gene IL15 and glioblastoma.