Consistent with our findings, another study reported that SREBP-1 was overexpressed in chemoresistant colorectal carcinoma (CRC) samples, and that SREBP-1 overexpression downregulated the expression of caspase 7, decreased CRC cell sensitivity to gemcitabine, and was positively correlated with a poor prognosis. The gene discussed is CASP7; the disease is colorectal carcinoma.