SLC2A4 and Hyperglycemia: The profound changes induced by overexpression of GLUT4 associated with hyperglycaemia could no longer avoid the activation of cell death mechanisms, proved by increased levels of apoptosis (1.7-fold more, WT30L vs. KE230L, p < 0.0001/1.6-fold more, KE220L vs. KE230L, p < 0.0001, one-way ANOVA) (Figure 6B).