The first objective of this work was to sequence the promoter and the complete LGALS1 gene (introns and exons) in 53 EA patients to identify tag single nucleotide polymorphisms (SNPs) that would allow us to infer the genetic variability of LGALS1 and that had minor allele frequencies (MAF) > 0.1 in order to test them as biomarkers in arthritis (Figure S1). This evidence concerns the gene LGALS1 and Arthritis.