CXCL1 and inflammatory bowel disease: CXCL1 expression in normal mucosa is expressed mainly in crypts [147]; however, in inflammatory bowel disease, CXCL1 expression occurs in pericrypt myofibroblasts [148], epithelial cells [147,148,149], enteroendocrine cells [150] and in inflammatory cells such as macrophages [148] and granulocytes [149].