Specifically, the HER2E subtypes are similar to HER2+/HER2E tumors but lack the amplification/ overexpression of the HER2 amplicon (ERBB2 and GRB7); on the other hand, the basal-like subtypes are similar to triple-negative breast cancers [5,6]. The gene discussed is ERBB2; the disease is triple-negative breast carcinoma.