CXCL8 and lymphangioleiomyomatosis: We demonstrated that LAM/TSC cells not only express and secrete more IL-8 than PLFs, but they are also able to cause a significant increase of IL-8 mRNA levels and IL-8 secretion in PLFs grown in LAM/TSC cell CM, while PLF CM does not cause any alteration in IL-8 expression and secretion.