Tumour-derived exosomes contain molecules similar to those present in TME responsible for immunosuppression such as TGFβ [204], FasL [211], PD-L1 [212], adenosine [206], survivin [213], and ligands for NKG2D [214], all with high potential to alter NK cell antitumour capabilities. Here, BIRC5 is linked to neoplasm.