MBOAT7 and metabolic dysfunction-associated steatotic liver disease: Interestingly, the presence of the MBOAT7 rs641738C>T risk variant, which leads to reduced membrane-bound O-acyltransferase domain containing 7 (MBOAT7) mRNA and protein levels, is associated with elevated levels of LPI in the liver and consistently with enhanced fibrosis development during NAFLD [101,102].