KCa3.1, encoded by Potassium Calcium-Activated Channel Subfamily N Member 4 (KCNN4) [19], has been reported to be highly expressed in various cancers including HCC [20,21,22,23,24,25,26,27], affecting cell metabolism, and reducing cell motility in glioblastoma derived CSCs [28,29]. The gene discussed is KCNN4; the disease is glioblastoma.