In addition, oral administration of myricetin-3-O-b-D-lactose sodium salt (M10), a derivative of myricetin, also exhibited preventive effect against ulcerative colitis through inhibiting the activation of IL-6 and TNF-α pathway, and phosphorylation of JAK2, STAT3, and NF-κB [55]. The gene discussed is TNF; the disease is ulcerative colitis.