Our present findings indicate that the HMGA1 gene expression level correlated with expression of both CDK1 and PPARG in lung adenocarcinoma and squamous cell carcinoma but not in normal lung tissue; this supports the findings that the interaction the HMGA1 with these CDK1 and PPARG are important for lung carcinogenesis. The gene discussed is HMGA1; the disease is lung adenocarcinoma.