In cancer, DLK1 acts as an oncogene, and elevated expression has been reported in endocrine and non-endocrine malignancies including prostate and ovarian cancers, neuroblastoma, pancreas and colon adenocarcinomas, non-small and small cell lung cancer, HCC, and Wilm’s tumor [50]. The gene discussed is DLK1; the disease is hepatocellular carcinoma.