CADM1 and small cell lung carcinoma: In conclusion, based on currently available evidence, we suggest a mode of action whereby MF-CADM1-specific IgG-based antibody can promote the efficient recruitment of T cells by interactions between the Fc region of the antibody and Fc gamma receptors expressing on T cells and redirect the activated T cells proximal to the membrane surface of MF-CADM1-expressing SCLC cells, resulting in potentiating T cell-mediated SCLC cell death.