There were significant differences in sex (p = 0.032), BMI (p = 0.001), number of teeth (p < 0.001), ABL (p < 0.001), hs-CRP (p < 0.001), and periodontal disease severity classification (p < 0.001) between the type 2 diabetic group and the non-diabetic group. This evidence concerns the gene CRP and periodontal disorder.