CPEB3 and hepatocellular carcinoma: However, co-transfection of miR-9-5p inhibitors, FOXO1 overexpression plasmid, and CPEB3 shRNA significantly increased the growth of hepatoma xenografts, similar to the effect of transfection with CPEB3 shRNA alone (Figure 5B), suggesting that in the case of CPEB3 silencing, the effects of promoting CPEB3 expression by miR-9-5p silencing and FOXO1 overexpression were masked.