We identified that FOXO1 directly regulates CPEB3 transcription by ChIP-Seq assays, Western blot (Figure 4A,D) and luciferase reporter in HepG2 cells (Figure 4E), although the regulation was not significant in Bel7402 cells (Figure 3A) and tumor tissues (Figure 5G, right). This evidence concerns the gene CPEB3 and neoplasm.