Overexpression of LSD1 messenger RNA (mRNA) and excess LSD1 protein have been observed in various malignancies, including neuroblastoma, squamous-cell carcinoma, Ewing sarcoma, AML, neuroendocrine tumors, breast cancer, prostate cancer, bladder cancer, small-cell lung cancer, and colorectal cancer [63,64,67,72,73,74]. The gene discussed is KDM1A; the disease is colorectal cancer.