Knockdown of integrin β3 significantly inhibited AXL and nuclear YAP expression, which could be rescued by activation of YAP in HCC827 ER and HCC4006 ER cells (Figure 5E,F), indicating that YAP participated in the regulation of AXL expression by integrin β3 in NSCLC cells (Supplemental Figure S2). Here, AXL is linked to non-small cell lung carcinoma.