However, under HF diet (CTRL HF vs. VDD HF) in males, we observed that two important pathways for adipose tissue biology [20], i.e., “NF-κB activation by viruses” and “p38 MAPK Signaling” were upregulated, suggesting that VDD exacerbated inflammation mediated by HF diet. The gene discussed is NFKB1; the disease is hydrops fetalis.