SPARC and type 2 diabetes mellitus: In skeletal muscle, the expression of MSTN (or GDF8, encoding myostatin) were 1.7-fold increased (unadjusted p = 0.03) in T2D, whereas the expression of other putative myokines DCN, SPARC, IL6, IL10, IL15, ANGPTL4, FGF21, FGF2, FSLT1, LIF, CHI3L1, GDF15, BDNF, or CTGF did not differ between groups (all FDR > 0.1).