PTPRC and steatosis: Function improved, time-dependent: AST, ALT (reduced 30–50%), ALB, BUN (30% reduction at highest dose) Histology improved, time-dependent: fibrosis, PCNA Gene expression in liver, time-dependent: TGFB1, COL I, ACTA1, IL1B, INFG Gene expression in liver not improved, time-dependent: TNF alpha Function improved dose-dependent: AST (1 dose level), ALT, ALB (1 dose level), BUN (1 dose level) Histology improved, dose-dependent: fibrosis, CD45+ cells Histology not improved, dose-dependent: steatosis Engraftment: pos by alpha sat-ch17