GOLM1 promotes HCC, glioma and prostate cancer proliferation and growth through the regulation of the EGFR/PDGFRα/RTK signaling pathway, thus resulting in the activation of PI3K/AKT/mTOR signaling cascade and in the positive feedback loop, already described in the previous section [31,32,33,34,39]. This evidence concerns the gene AKT1 and hepatocellular carcinoma.