Both miR-15a-3p and miR-16-1-3p target two conserved sites in the 3′-UTR of Twist1 to reduce the mRNA and protein levels of biomarkers, including N-cadherin, α-SMA, fibronectin, and MMP9, so as to attenuate the migration and invasion of gastric cancer cells [84]. The gene discussed is CDH2; the disease is gastric cancer.