In the subset of 340 BRCA1/2-negative patients with mBC, the overall prevalence of PVs in patients with a BC/OC FH was 9.8% (23/235), and that in patients without a BC/OC FH was 8.8% (9/102) (23/235 vs. 9/102; Fisher’s exact test p = 0.84). This evidence concerns the gene BRCA1 and breast cancer.