To address this question, we first examined CD44 and TF expression in different EMT cellular models that previously allowed us to associate TF expression to EMTs [23,24]: (i) in well-known invasive EMT+ MDA-MB-231 and Hs578T versus non-invasive EMT− MCF7 and T47D human breast tumor cell lines, (ii) in MDA-MB-468 known to be induced to EMT by EGF and (iii) in the MDA-MB-468 cells expressing a doxycycline-inducible vector for Snail (MDA-MB-468-iSnail) in which we previously reported an induction of TF associated to EMT after doxycycline treatment [23]. The gene discussed is EGF; the disease is breast neoplasm.