A subsequent study showed inhibition of induction of apoptosis in resveratrol-treated ACHN and 786-O RCC cell lines as observed through significantly downregulated expressions of NLR family pyrin domain containing 3 (NLRP3), an inflammasome, leading to decreased anti-apoptotic caspase-1 expression and increased pro-apoptotic caspase-3 expression [75]. Here, CASP3 is linked to renal cell carcinoma.