KLK3 and posterior cortical atrophy: The exosomes-derived gene expression profile showed a higher predictive value than PSA (AUC 0.73; 95% CI, 0.68–0.77 vs. AUC 0.63; 95% CI, 0.58–0.68) in the identification of high-grade PCa patients with respect to intermediate positive and negative biopsy from PCa patients.