Lastly, Aqeilan et al. [93] demonstrated that miR-15 and miR-16 are involved in the multi-drug resistance of ovarian cancer cells by acting on Bcl-2, while Luo et al. [94] reported the tumour suppressing role of miR-126 in cancer SKOV3 cells, by demonstrating a miR-126-mediated P21 (RAC1) activated kinase 4 (PAK4) down-regulation. Here, BCL2 is linked to neoplasm.