An accumulating number of recent studies have reported the mutual interaction between miRNAs and key components of various signaling pathways including epidermal growth factor, Wnt/β-catenin, nuclear factor kappa B (NF-κB), and PI3K signaling pathways in developing MDR in glioblastoma [168,169,170,171,172,173]. The gene discussed is NFKB1; the disease is glioblastoma.