To identify the significance of the allelic ratio and NPM1 status in FLT3-ITD-mutated AML, the post-HSCT outcomes for patients of different combinations of FLT3-ITDhigh or low/NPM1wt or mut, belonging to INT and ADV risk by ELN 2017, were separately analyzed in this study. Here, NPM1 is linked to acute myeloid leukemia.