The protein level of PCNA (a marker for cell proliferation), N-Cadherin (a marker for EMT transition in tumorigenesis), β-catenin (a marker in advanced colorectal carcinoma), and MMP-9 (a key regulator for EMT-related metastatic capability) were further detected in these tumor tissues by immunohistochemistry. The gene discussed is MMP9; the disease is neoplasm.