The median age at baseline was 59 years (Supplementary Materials Figure S1), 293 (59.8%) were male and 197 (40.2%) female, 51 (11% of 482 patients with available data) had IDH1 or IDH2 mutations detected in their tumours, and 234 (51% of 456) of patients had methylation of the MGMT promotor. The gene discussed is IDH1; the disease is neoplasm.