In the Radon France study, an ecologic study, the prevalence of molecular alterations has been positively correlated with the indoor radon risk area based on the official French map (Institut de Radioprotection et de Sûreté Nucléaire, IRSN, France) in a cohort of 116,424 patients with NSCLC tested for EGFR, BRAF, HER2, KRAS, ALK, ROS1 on the 28 French Platform led by INCa (French National Cancer Institute). Here, ALK is linked to non-small cell lung carcinoma.