AKT3 and medulloblastoma: Of note, from these 122 and 13 de-regulated mRNAs and circular RNAs only 33 and 1, respectively, were present within the de-regulated mRNAs and circular RNAs in the SHH medulloblastoma subtype compared to cerebellum (Files S1 and S2), with some, e.g., circular RNA AKT3, being de-regulated in the opposite direction.