SOX2 and nasopharyngeal carcinoma: In our previous studies, ICG-001-mediated blockage of canonical Wnt/β-catenin signaling could inhibit the growth of CSC-enriched NPC tumor spheres via the miR-145/SOX2 axis [27] and inhibit the migration of NPC cells via the miR-150/CD44 axis [28] and the miR-96/EVI1/miR-449a axis [29].