The data established the presence of two well-defined clusters of strong association: one group consisting of BIRC5, EGFR, KRT18, SPP1, TNC, TWIST1, TRPM4, VEGFA, and ZEB1 genes and the second of TRPV6 and VIM, suggesting a suitable gene model for CTCs from BC patients (Figure 5B,C and Figure S3). Here, SPP1 is linked to breast cancer.