Studying the ENT3 regulation of BA-mediated ER stress signaling in hematopoietic progenitors and precursors constitutes an important area of investigation both from a fundamental science point of view to understand hematopoiesis, and from a translational science perspective to treat anemia in scenarios such as SLC29A3 genetic disorders and nucleoside analog-induced hematological toxicities. Here, SLC29A3 is linked to anemia.