Consequent expression analyses in the prostate cancer tissues showed a significantly diminished expression of the imprinted genes PLAGL1/ZAC1 (OMIM 603044), MEG3 (OMIM 605636), NDN (OMIM 602117), CDKN1C, IGF2, and H19, whereas KCNQ1OT1 was significantly overexpressed [49]. Here, IGF2 is linked to Familial prostate cancer.