More research is also needed to elucidate the exact molecular mechanism underlying the link between DHRS7 and EGFR, to assess whether the inverse correlation of DHRS7 and EGFR expression can be replicated in metastatic PCa samples, to test whether DHRS7 expression might help to discriminate Gleason score- and age-matched patients with different prognosis, and to identify the physiological DHRS7 substrate(s). The gene discussed is DHRS7; the disease is posterior cortical atrophy.