MMP2 and Familial prostate cancer: At the same time, it dysregulated the expression of a wide range of miRNAs involved in the development and progression of prostate cancer, e.g., miRNA-29b, which regulates the expression of the proteins E-cadherin, N-cadherin, Snail, Twist and matrix metalloproteinase-2 (MMP2) involved in the metastatic process [38].