A higher prevalence of LD with an Epm2B mutation was reported in mature miniature wirehaired Dachshund dogs who commonly presented with signs of panic attacks, reflex and spontaneous myoclonus hypnic myoclonus, dementia, impaired vision and blindness, aggression, deafness, and fecal/urinary incontinence. The gene discussed is NHLRC1; the disease is Anxiety.