RHO and multiple sclerosis: In the “inhibition of remyelination in multiple sclerosis: regulation of cytoskeleton proteins”, RhoA binds to protein kinase 2 (ROCK2), which contains association with Rho and promotes phosphorylation and activation of protein phosphatase 1 (MLCP (reg))/protein phosphatase 1, isoenzyme beta (MLCP) (cat)), with dephosphorylation of Myosin II regulatory light chains (MRLC and MELC) [91,92].