COL1A2 and osteogenesis imperfecta: In this report, we first describe a Chinese family in which the proband and his affected father carried heterozygous mutations in the COL1A2 gene (OMIM: 120160; c.3304G > C; p.Gly1102Arg) and FBN2 gene (OMIM: 612570; c.4108G > T; p.Glu1370*) that caused a significantly more severe phenotype of OI.