ACE and heart failure: There were significant differences between the iCS and sCS groups in terms of sex, angiotensin-converting enzyme (ACE) levels, soluble interleukin-2 receptor (sIL-2R) levels, LVEF, the frequency of LVEF < 50%, number of major criteria met, the positive rate of EMB, the New York Heart Association functional classification class, and the frequency medical therapy for heart failure.