The migration and invasion of DHLF-IPF cells, which were suppressed by HDAC3 inhibition, were restored—with increases of 608-1230% and 34.3-312%, respectively—after transfection with HDAC3 and FOXA1 siRNAs under hypoxia (Fig. 4j and k). This evidence concerns the gene HDAC3 and idiopathic pulmonary fibrosis.