HDAC3 and pulmonary fibrosis: In our study, the HDAC3-miR224-FOXA1 axis effectively regulated the migration and invasion of fibroblast cells under hypoxia, suggesting that the HDAC3-miR-224-FOXA1 axis may be involved in pulmonary fibrosis by regulating the migratory and invasive properties of human fibroblast cells under hypoxic conditions.